Abstract by Greg Felsted
Chemistry and Biochemistry
Thermal Gradient Coupling to Solvating Gas Chromatography
Solvating gas chromatography is a form of chemical separation by use of supercritical fluids across a pressure drop. Solvating gas chromatography has demonstrated a large capacity for improved separation quality due to a drop of solvating power of the mobile phase as pressure decreases down the column. The utility of this technique is limited volatility and size of the analyte. By coupling solvating gas chromatography to a thermal gradient, a wider set of molecules can be separated by this technique while limiting separation quality loss. Preliminary results suggest improved separation times with minimal resolution losses. Further work is being done with larger molecules.